Micro-/anophthalmia observed in mouse families administered with 5-Azacytidine.

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5-azacytidine: microbiological assay in mouse blood.

A 6-chloropurine-resistant strain of Escherichia coli has been used to develop a microbiological assay for the estimation of 5-azacytidine distribution in mouse tissues.

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A Novel Missense Mutation in the ALDH13 Gene Causes Anophthalmia in Two Unrelated Iranian Consanguineous Families

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Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells

Previous studies showed that downregulation of pyrimidine salvage underlies resistance against 5-azacytidine (AZA), indicating an important role for de novo pyrimidine synthesis in AZA resistance. Because de novo pyrimidine synthesis is inhibited by the immunomodulator teriflunomide and its pro-drug leflunomide, we examined the effect of combined treatment with AZA and teriflunomide on AZA resi...

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CNS Involvement in AML Patient Treated with 5-Azacytidine

Central nervous system (CNS) involvement in acute myeloid leukemia (AML) is a rare complication of the disease and is associated with poor prognosis. Sometimes the clinical presentation can be unspecific and the diagnosis can be very challenging. Here we report a case of CNS infiltration in a patient suffering from AML who presented with normal complete blood count and altered mental status.

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ژورنال

عنوان ژورنال: Journal of Toxicologic Pathology

سال: 1994

ISSN: 0914-9198,1881-915X

DOI: 10.1293/tox.7.409